"By imaging the whole transcriptome at the individual transcript level and advancing sensitivity across any in situ RNA assay, these developments in CosMx represent a historic milestone in the study ...

In regenerative science, B7-33's potential to influence fibroblast activity and collagen turnover suggests possible implications for tissue repair and wound healing. Given that fibrosis is often a ...

Eating patterns can override genetic risk for type 2 diabetes. Discover the 4 dietary approaches proving most effective at ...

The thymus is a crucial training ground for T-cells, the body's "white knights," where they learn to battle the various diseases they may encounter. Thymic function shrinks to nearly nothing as we age ...

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science ...

Researchers at the National Institutes of Health (NIH) have discovered clues as to how our bodies turn sensations such as ...

Research on guinea pig embryos uncovers similarities to human embryogenesis, advancing understanding of preimplantation ...

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Activation of the mTORC1 signaling pathway can inhibit autophagy, but it promotes synthesis of nucleotides, proteins and lipids to increase cell growth and proliferation. mTORC2 is predominantly ...

In MASLD and MASH, TGF-β signaling contributes to hepatocyte lipid accumulation, cell death and fibrosis progression through both Smad and non-Smad pathways. In HCC, TGF-β and other TGF-β-SF cytokines ...