used genetically engineered mice to tackle the questions from the Israeli researchers. "We found the new cells were scattered in the medullary region of the thymus," she said. "This has ...

UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, the tissue can be used to foster ...

The finding, based on studies conducted in mice, could lead to better understanding of the drivers of autoimmune problems in humans, the authors say. The cells in the medulla region of the thymus ...

to revive the structure and function of the thymus in old mice. The thymus sits in front of the heart and is where T cells mature; its age-related decline is associated with cancer, infections and ...

Cells from a mouse embryo were reprogrammed to look like thymus cells and then transplanted into a mouse. The cells formed a replacement organ with the same structure, complexity and function as a ...

"These cells mature in the thymus, an organ just above the heart, where they 'get educated' to not attack the body." Study co-author Jessica Lancaster, a postdoctoral researcher, and Ehrlich used a ...

The experiments showed mice without a thymus had immunodeficiency ... and foreign antigens. After the T cells leave the thymus, thymosin ensures they undergo complete maturation.

This study — conducted in a mouse model — also showed that this increase in autoreactive T cells was mediated by the adverse effects of vitamin D deficiency on cells in the thymus, the ...

They have even grown and transplanted whole thymus glands in mice. Yet, no one has developed some from human cells that are capable of holistically recapitulating the organ’s functions.

Researchers at the Francis Crick Institute have identified stem cells in the human thymus for the first time. These cells represent a potential new target to understand immune diseases and cancer and ...

Are the M cells doing the same thing in the thymus in terms of organization and function? That’s what we would like to know.” Del Castillo, who is working toward her doctoral degree in biomedical ...