Proteolysis Targeting Chimeras (PROTAC): Bifunctional molecules designed to induce the degradation of specific proteins by harnessing the ubiquitin-proteasome system. Celastrol and Its Effects on ...

The proteasome functions in one of the main protein-degradation pathways in cells, the ubiquitin–proteasome system 6. In this pathway, a multi-enzymatic cascade covalently links the small ...