Using an inexpensive electrode coated with DNA, MIT researchers have designed disposable diagnostics that could be adapted to ...

When fused to an enzyme, Cas9 and Cas12 can make targeted chemical changes to DNA at locations determined by the gRNA sequence.

MIT has developed a DNA sensor that can detect HPV and HIV infections through voltage changes. The sensor is durable and ...

What if cancer, HIV could be diagnosed at home and that too for less than the cost of a bus ticket? MIT researchers have ...

The CRISPRtool is a deep learning-based adaptive ensemble method, integrating context-based sequence features with specific cell line characteristics to enhance the design of on-target sgRNAs within ...

Background Genetic engineering of animals has been recently revolutionized with the development of genome editing tools such as CRISPR-Cas9 and other CRISPR systems like Cas12 and Cas13. Genome ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence.

Genome editing in melon (Cucumis melo L.) remains a significant challenge due to the inefficiencies associated with conventional cell culture-based transform ...