While cancer-associated fibroblasts (CAFs) significantly influence tumor progression, their temporal dynamics remain poorly understood. We investigated time-dependent interactions between non-small ...

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the ...

This new article publication from Acta Pharmaceutica Sinica B, discusses targeting stem-property and vasculogenic mimicry for sensitizing paclitaxel therapy of triple-negative breast cancer by ...

Background: EMT is a phenotypic description of cancer cells that include loss of cell adhesion, increased motility, invasion, and chemoresistance. EMT gene signature is a poor prognostic feature in ...

Epithelial-to-mesenchymal transition (EMT) primarily initiates invasion, with EMT marker expression often used to gauge tumor invasiveness. The Boyden chamber migration assay serves as the gold ...

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the ...

Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the ...

Immunologists at UNIGE have revealed a previously unknown anti-tumor role of CD4 T lymphocytes, marking a breakthrough that ...

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine ...

Recent research on MCL-1, a critical protein that is an attractive target for cancer drug development, helps explain why some ...