Using a similar EMT detection system in the cancer cells, TFs, such as SNAIL1, SNAIL2, TWIST1 and ZEB1, were identified as independently responsible for an incomplete or partial EMT programme in ...

EMT is the process whereby epithelial cells are transformed into mesenchymal cells. “EMT is a transient, reversible process of cell de-differentiation where cancer cells transit between various ...

Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the ...

While cancer-associated fibroblasts (CAFs) significantly influence tumor progression, their temporal dynamics remain poorly understood. We investigated time-dependent interactions between non-small ...

Epithelial–mesenchymal transition (EMT) is a phenomenon during which cells undergo transition from an epithelial-to-mesenchymal phenotype. 3 As cancer cells acquire the ability to invade and to ...

This new article publication from Acta Pharmaceutica Sinica B, discusses targeting stem-property and vasculogenic mimicry for sensitizing paclitaxel therapy of triple-negative breast cancer by ...

Transforming growth factor-β (TGFβ) is already known to promote metastasis by enhancing EMT and invasiveness in primary carcinomas: once cancer cells reach the site of metastasis, TGFβ enhances ...

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the ...

Our ability to reverse EMT by reintroducing miR-200 into cancer cells gives rise to the hope that this miRNA family might be useful in reversing cancer progression" explains Dr. Peter. Journal ...

Recently, Dr. Feng Lin from College of Engineering, Peking University, published a research paper entitled "Mechanical transmission enables EMT cancer cells to drive epithelioid cancer cell ...

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used. Skip to content Menu ...