Calcium-activated proteolysis by calpain is a candidate to participate in this form of pathology because it is activated under ischemic conditions and its activation results in the degradation of ...

Interleukin-27 (IL-27) is a member of the IL-12 family. The gene encoding IL-27 is located at chromosome 16p11. IL-27 is considered as a heterodimeric cytokine, which consists of Epstein–Barr virus ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Ubiquitylation is involved in various physiological processes, such as signaling and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The cGAS-STING signalling pathway has a ...

Time-lapse microscopy in wild-type and mutant PNs reveals that Gjd2b puncta promote the elongation of branches and that CaMKII may be a critical mediator of this process. These results demonstrate ...

Cell migration is central to a wide variety of physiological and pathophysiological processes. These include morphogenetic movements during embryogenesis, migration of inflammatory cells to sites of ...