News

Hosted on MSN28d
Bladder macrophages form immune barrier against bloodstream infections, study finds
By analyzing the heterogeneity of bladder mucosal macrophages under homeostatic conditions, the researchers identified a novel subpopulation of CX3CR1 hi macrophages localized beneath the ...
ahajournals.org22d
Choroidal Neovascularization Is Suppressed With Activation of TREM2 in Mononuclear Phagocytes
46–48 Further investigation is needed with TREM2 KO mice with specific Cre drivers such as LysM, CD11b, or CX3CR1 Cre to determine TREM2 function in mononuclear phagocytes. Furthermore, a rescue ...
gut.bmj10d
Niche-specific functional heterogeneity of intestinal resident macrophages
Correspondence to Professor Guy Boeckxstaens, Translational Research in Gastrointestinal Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing (Chrometa), KU Leuven, Leuven, ...
Frontiers10d
The Inflamed Brain in Schizophrenia: The Convergence of Genetic and Environmental Risk Factors That Lead to Uncontrolled Neuroinflammation
Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay between genetic and environmental risk factors. The immune system is now known to play vital roles in nervous ...
Frontiers17d
Deciphering T-cell exhaustion in the tumor microenvironment: paving the way for innovative solid tumor therapies
In solid tumors, the tumor microenvironment (TME) is a complex mix of tumor, immune, stromal cells, fibroblasts, and the extracellular matrix. Cytotoxic T lymphocytes (CTLs) constitute a fraction of ...
gut.bmj14d
Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway
Correspondence to Youming Li and Professor Chaohui Yu, Department of Gastroenterology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang, China; ...