Microglia, Pediatric Neurology, Autism Spectrum Disorder, Epilepsy, Neuroinflammation, Neurodevelopment Kaur, H. (2025) The Role of Microglia in Pediatric Neurological Disorders. Neuroscience and ...

This, in turn, upregulates CX3CL1, an immune signal that attracts inflammatory cells, exacerbating arterial plaque formation.” After 4 weeks of the aspartame diet, the mice started to develop ...

The researchers identified a signal molecule called CX3CL1 that became more active as insulin levels rose. Removing CX3CL1 receptors in the mice stopped the dangerous buildup of plaque in arteries – ...

Next, they investigated how exactly elevated insulin levels lead to arterial plaque buildup and identified an immune signal called CX3CL1 that is especially active under insulin stimulation.

Next, they investigated how exactly elevated insulin levels lead to arterial plaque buildup and identified an immune signal called CX3CL1 that is especially active under insulin stimulation. “Because ...

NK cells were recruited to the ischemic region through the IP-10/CXCR3 and CX3CL1/CX3CR1 axis (Zhang et al., 2014). Additionally, NK cells are also recruited to the CNS by chemokines such as CCL2 and ...

2015). The CX3CL1/CX3CR1 and CCL2/CCR2 signaling pathways have been shown to play a major role in recruiting macrophages into the cochlea. However, these two chemokines are still not enough to explain ...

Adult-born granular cells (abGCs) in microglia-depleted mice have lower spine density, but not spine size, compared to abGCs in WT control mice. Together these findings suggest that microglia have ...

Impact of stress on diseases including gastrointestinal failure is well-known, but molecular mechanism is not understood. Here we show underlying molecular mechanism using EAE mice. Under stress ...