A first-in-human clinical trial tests a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers.

Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) ...

Researchers have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers. The results show ...

Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing ...

For decades, scientists and surgeons around the world have been trying to solve the organ donor crisis. The answer could be ...

Mammary gland fibroblasts are highly plastic and transition through distinct states during development and disease. A new ...

A few years ago, the introduction of CRISPR technology marked a significant breakthrough in the scientific community. Derived from a component of the bacterial immune system, CRISPR enables precise ...

State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China ...

The study applied a new approach that installed hairpin internal nuclear localization signal sequences (hiNLS) at selected sites within the backbone of CRISPR-Cas9. This approach contrasts with ...

While CRISPR/Cas9 has been the cornerstone of gene editing, it faces challenges such as off-target effects and difficulties with in vivo applications. Brink Therapeutics aims to address these ...

To connect our findings to cell polarity studies of the nematode Caenorhabditis elegans zygote, we reconstituted a 5-node network where a 4-node circuit with full mutual inhibitions between anterior ...