CRISPR-Cas9 genome editing exploits the CRISPR ... system to correct the point mutation in a preclinical RP mouse model. In vivo treatment achieves genome editing and restores mice vision.

Congenital hearing loss refers to impaired auditory function that occurs due to genetic causes. GJB2 is the gene responsible ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

An R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent ...

R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent ...

Congenital hearing loss refers to impaired auditory function that occurs due to genetic causes. GJB2 is the gene responsible ...

Congenital hearing loss refers to impaired auditory function that occurs due to genetic causes. GJB2 is the gene responsible for approximately half of ...

A new CRISPR-based technology, called RIDE, is a leap forward for this trail-blazing technology. With the precision of a ...

Expanding CRISPR's Potential Since its discovery, CRISPR (“Clustered Regularly Interspaced Short Palindromic Repeats”), which ...

The results of this work reveal how an alternative splicing mechanism regulates an essential factor for neuronal identity.

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...