A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that ...

A research team has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than ...

Base editors, which convert one nucleotide to another without a double-strand DNA break, have the potential to treat diseases caused by mutant genes. One drawback, though, is that the DNA that encodes ...

R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent cells and leading to syndromic hearing loss. In a new experimental study, ...

The global humanized liver mice model market is on a strong growth trajectory, fueled by the increasing prevalence of liver ...

Classical CRIPSR To fix the dysferlin mutation, Escobar uses CRISPR-Cas9, which is often described as "gene-editing scissors" ...

Feb. 13, 2025 — A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Charlene earned her MSc and PhD in cell biology from the University of Toronto and currently serves as an assistant science editor for The Scientist's Creative Services team. View Full Profile. Learn ...

Targeted CRISPR lipid nanoparticles eliminated 50% of tumors in mice with head and neck cancer. Researchers from Tel Aviv University (Israel), led by Razan Masarwy, have investigated utilizing CRISPR ...