CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

Using CRISPR-Cas9 edited iPSC-derived MN models ... For MN survival experiments, lentiviral SYN1-GFP (PZ196, Addgene) was added to MNs in suspension prior to seeding onto ImageLock 96 well plates ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. An evolutionarily conserved micropeptide, ...

The best free Adobe Illustrator alternatives serve up all the essential tools artists need for vector editing without requiring a Creative Cloud subscription. There's ...

Ar­bor Biotech­nolo­gies, a start­up found­ed by CRISPR pi­o­neer Feng Zhang nine years ago, has closed a $73.9 mil­lion Se­ries C fi­nanc­ing to bring its first … ...

State Key Laboratory of Food Nutrition & Safety, Tianjin University of Science & Technology, Tianjin 300457, P. R. China Key Laboratory of Industrial Fermentation Microbiology (Ministry of Education), ...

eliminate the need for immune cell depletion and have the potential to improve efficacy and safety through advanced lentiviral vector technology. The vector has modifications which deliver specificity ...

AstraZeneca has entered the “off-the-shelf” cell therapy space, penning a $1 billion deal to acquire EsoBiotec and its lentiviral vector platform. The deal will see AstraZeneca scoop up all ...

The development of precise and efficient delivery systems is pivotal for advancing CRISPR/Cas9 gene-editing technologies, particularly for therapeutic applications. Engineered metal–organic frameworks ...