NEW YORK – In cell and gene therapies, the genetic machinery is key to producing the proteins missing or dysregulated in a disease, but whether the therapeutic cassette reaches target cells and how ...

All experiments were performed in triplicate. The pLenti-CRISPR-V2 vector was used for CRISPR/Cas9-mediated gene knockout in CAL27 and FaDu cell lines. Briefly, lentivirus vector expressing CASP3 gRNA ...

The agreement grants Jumpcode access to ERS' CRISPR/Cas9 patent portfolio, empowering the company to advance the sensitivity and efficiency of next-generation sequencing (NGS) and expand ...

Professor Amrolia selected ViroCell to manufacture the lentiviral vector for this novel CAR T-cell therapy based on its track record for delivering high quality vector. Through this relationship ...

A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...

Built around one of the most prolific academic viral vector manufacturing teams ... Focused initially on manufacturing lentivirus and gamma-retrovirus vectors, ViroCell enables clients to start ...

That’s the view of analysts at Jefferies, who suggest it could “re-ignite concerns over the use of lentiviral vectors and the risk of secondary (vector-mediated) cancer". Cancer is a perennial ...

We custom design each of our therapies to address the underlying cause of disease and have developed in-depth and effective analytical methods to understand the safety of our lentiviral vector ...

Apr. 15, 2025 — Wildflowers growing on land previously used for buildings and factories can accumulate lead, arsenic and other metal contaminants from the soil, which are consumed by pollinators ...

In this study, we demonstrated the exploitation of CRISPR/Cas9 as a high precision system for editing the ... All sections were mounted using the Vectashield antifade mounting medium containing DAPI ...