Building a gene editor took months. With CRISPR even high-schoolers can get hold of editing systems in the time it takes to order RNA sequences online and have them shipped by FedEx. In a short while ...

This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...

Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradatio ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...

In 2020-2021, a mysterious skin disease affected fishermen in Senegal. High levels of Portimine A toxin, produced by the ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

Oshi no Ko manga came to an end in 2024, and its conclusion caused quite a stir within the community. Many fans were displeased with the way Asa Akasaka handled the story, but the author had ...

Based on the manga by writer Aka Akasaka and artist Mengo Yokoyari, Oshi no Ko has a pretty wacky premise, involving a doctor and his patient who die and get reincarnated as the twin children of a ...

Both Cas9 and Cas12a cleave DNA, but they differ in how they cut the molecule.