The Economist5h
Gene editing has arrived
Building a gene editor took months. With CRISPR even high-schoolers can get hold of editing systems in the time it takes to order RNA sequences online and have them shipped by FedEx. In a short while ...
Harvard Medical School1d
Creating the World’s First CRISPR Medicine, for Sickle Cell Disease
In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...
AZoLifeSciences on MSN1d
Using CRISPR-Cas9 Gene Editing for Chromosomal Rescue in Down Syndrome
Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro ...
eLife2d
Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish
This important study examines the role of pericytes in patterning the zebrafish blood-brain barrier (BBB) and controlling its permeability. Using pdgfrb mutant zebrafish models lacking brain pericytes ...
eLife4d
A Commander-independent function of COMMD3 in endosomal trafficking
Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradatio ...