It allows the evaluation of the quality of gene editing experiments using targeted next generation sequencing (NGS) data (`targeted`) as well as the discovery of important genes from knock-out or ...

It allows the evaluation of the quality of gene editing experiments using targeted next generation sequencing (NGS) data (`targeted`) as well as the discovery of important genes from knock-out or ...

The company’s lead product candidate is CASGEVY, an ex vivo CRISPR/Cas9 gene-edited cell therapy for treating patients suffering from transfusion-dependent beta-thalassemia, severe sickle cell ...

This is an important study utilizing innovative CRISPR based approaches demonstrating the role of the KLF family of transcription factors in the post natal maturation of cortical projection neurons.

To address this, we developed a CRISPR/Cas9 loss-of-function library targeting nuclear-encoded ... Recessive mutations in RTN4IP1 have been identified through whole-exome sequencing in several ...

Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea Center for Natural Product Systems Biology, Korea Institute of Science and Technology (KIST) ...

The team of biologists overcame this issue by repurposing CRISPR—a revolutionary gene ... each type of microbe and reading these using DNA sequencing, we can provide a clearer picture of the ...

Nucleic Acid R&D, RSBU LSSII, GenScript Biotech Corporation, 28 Yongxi Street, Nanjing 211100, Jiangsu, China ...

To address these challenges, we combined genome-scale CRISPR/Cas9 knockout screening, single-cell-CRISPR Purterb RNA sequencing (scRNA-seq), and AI-driven virtual screening to identify novel ...