In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...
Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...
This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...
In addition, an auto-association background condition without target DNA (mouse cell lines transfected with sgRNA to locus 1) was included in the measurements of the non-repetitive region of MUC4 ...
CRISPR/Cas9 p53 knockdown and its control plasmids were kindly provided ... Four- to 5-week-old female BALB/c nude mice (SPF Biotechnology Co., Ltd., Beijing, China) were used in this study. The ...
For the first time, scientists have created a bi-paternal mouse – that is ... To address these limitations, the team used a CRISPR/Cas9-based gene editing technology to target 20 genes ...