CRISPR-Cas9 genome editing exploits the CRISPR-Cas ... Using a genome-wide CRISPR knock-out screen, the authors defined the repertoire of genes that are required for proerythroblast survival ...

The global humanized liver mice model market is on a strong growth trajectory, fueled by the increasing prevalence of liver ...

To strengthen the capacity of NK lymphocytes to eliminate tumors, researchers used CRISPR/Cas9, a genetic editing ... The results, both in vitro and in mice models, demonstrate that the ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have ... Yale scientists have developed a series of sophisticated mouse models using CRISPR ("clustered ...

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, United States; Department of Microbiology, UMass Chan Medical School, United States; ...

The development of precise and efficient delivery systems is pivotal for advancing CRISPR/Cas9 gene-editing technologies, particularly for therapeutic applications. Engineered metal–organic frameworks ...

Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ... Dec. 13, 2024 — Microorganisms produce a wide variety of natural products that can be ...

Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation ... interspaced short palindromic repeats (CRISPR-Cas9) ...

Glaucoma is a leading cause of irreversible blindness. In this study, we investigated if transplanted stem cells are able to rescue a glaucoma mouse model with transgenic myocilin Y437H mutation and ...

Because mice carrying the disease will die soon after birth, the gene-editing intervention needed to occur before delivery, say the authors. They injected CRISPR-Cas9 into the amniotic fluid of ...