The possibility of editing our genes once seemed more like science fiction than reality. Times have changed with the ...

However, mice implanted with human tumor cells that have not been ... The team used a molecular tool called CRISPR-Cas9 to knock out genes researchers believe could play a role in making tumors ...

A new study finds that gut-specific TM6SF2 depletion exacerbates liver fat accumulation and dysbiosis in mice on high-fat diets, highlighting its importance in gut-liver metabolic regulation.

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

TM6SF2 GKO mice fed an HFD showed elevated liver and intestinal lipid deposition compared to CON mice. The gut microbiota of HFD-fed TM6SF2 GKO mice exhibited a decreased Firmicutes/Bacteroidetes ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Genetic defects are exceedingly common, which is not surprising considering just how many cells make up our bodies, including our reproductive cells. While most of these defects have no or only ...