Industrial fermentation using bacteria, yeast and other microbes to produce specific products has the potential to reduce ...

Researchers at the Max Planck Institute for Evolutionary Anthropology have addressed a longstanding challenge in CRISPR ...

The personalized CRISPR treatment could be the future of gene therapy, but hurdles remain before everyone has access.

Genetic defects are exceedingly common, which is not surprising considering just how many cells make up our bodies, including our reproductive cells. While most of these defects have no or only ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Institute of Pathogenic Microbiology, Guangdong Provincial Center for Disease Control and Prevention, Guangdong Workstation for Emerging Infectious Disease Control and Prevention, Chinese Academy of ...

In­tel­lia’s CRISPR-based ther­a­py main­tained re­duc­tions in the lev­els of a mis­fold­ed pro­tein in the nerves of pa­tients with a rare dis­ease called transthyretin amy­loi ...

Interference No. 106,115 was the second interference between UC and Broad over patent rights to CRISPR-Cas9 technology in eukaryotic cells. The first interference concluded in 2018 after an appeal ...

The researchers used the gene scissors CRISPR/Cas9 to introduce various ALS-causing mutations into human stem cells, called iPS cells. From these, motor neurons, the nerve cells that are lost in ...

While the mutations studied do not lead to significant changes in GeoCas9 cleavage activity, the study provides convincing evidence for the role of allosteric mechanisms and interdomain communication ...

An infant with a rare genetic condition made headlines last week after successfully receiving personalised CRISPR therapy. Jacqui Wise summarises what we know so far about the breakthrough US doctors ...

When CRISPR was first introduced as a gene-editing tool in 2012, the world was in awe of all the possibilities it held — eventually earning its discoverers the Nobel Prize in Chemistry in 2020. Now, ...