Industrial fermentation using bacteria, yeast and other microbes to produce specific products has the potential to reduce ...

Researchers at the Max Planck Institute for Evolutionary Anthropology have addressed a longstanding challenge in CRISPR ...

Genetic defects are exceedingly common, which is not surprising considering just how many cells make up our bodies, including our reproductive cells. While most of these defects have no or only ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Nine years ago this month, researchers led by Harvard University’s David Liu reported on a new gene editing technique, a variation on CRISPR/Cas9 that they dubbed base ... creating unwanted mutations.

Cas9: CRISPR-associated protein 9 ... HDR uses a template strand to precisely repair a DSB, such that no mutations are introduced at the cleavage site. While this occurs naturally during the cell ...

Since the initial development of CRISPR-Cas9, researchers have introduced more precise gene-editing techniques ... This precision reduces the risk of unintended mutations and is particularly useful ...

Scientists introduced CRISPR to the world as a gene ... treated are removed from the patient's body, then Cas9 tool is applied to correct the mutation — or actually, trigger production of ...

there is a heightened risk of off-target mutations in areas distinct from the original target of CRISPR/Cas9. Credit: S. Nakada In a new study published in the journal Nature Communications, ...

However, the CRISPR/Cas9 method can also result in unintended DNA mutations that may have negative ... researchers led by Osaka University introduced a novel technique called NICER, which is ...

However, the CRISPR/Cas9 method can also result in unintended DNA mutations that may have negative ... researchers led by Osaka University introduced a novel technique called NICER, which is ...

Genome-editing technology centered on CRISPR-Cas9 has revolutionized the food and medicine industries. In the technology, Cas9 nuclease, an enzyme that cuts DNA, is introduced into the cell with a ...