Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

Use precise geolocation data and actively scan device characteristics for identification. This is done to store and access information on a device and to provide personalised ads and content, ad and ...

Evotec's insights into GPCRs and waveRAPID technology reveal new opportunities in drug discovery, focusing on orphan ...

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

Machine learning and supercomputing have brought about a revolution in computational drug discovery. More therapeutic candidates, like antibodies that bind to and fight the SARS-CoV-2 virus, can be ...

The expected concentration-dependent ligand binding curve was observed; however, the protein G-immobilized anti-HRP antibody resulted in substantially worse sensitivity and limit of detection (199 pM) ...

The work demonstrates a transformative step forward in profiling protein expression ... The implementation of CuRVE in this study integrates innovations that control antibody binding speed and ...

Dynamic light scattering is frequently utilized to assess the quality of protein aggregation ... the presence of several binding species generates binding curves that cannot correctly fit under ...

Oxysterol-binding protein (OSBP) and OSBP-related protein 4 (ORP4 ... biochemical assay procedures, and binding curves for all ligands (PDF) ...

Poxvirus membranes are organized into distinct binding and fusion domains. To facilitate fusion, the virus binding protein D8 actively curves host membranes to promote their contact with the virus ...