There are trillions of microbes in the gastrointestinal tract, and we are starting to learn more about the exact mechanisms ...

Liver, which is located in the abdomen, carries out a number of vital tasks, such as removing toxins, storing nutrients, breaking down drugs and alcohol, and creating bile, enzymes, and proteins.

While organoids aim to mimic human organs, the liver's repertoire of complex functions – and thus the energy it needs to operate – have made it challenging for researchers to grow organoids that ...

Scientists achieve breakthrough in liver research with mini organoids that grow a million-fold and stay functional for months.

The body's home-grown microbiota and bile acids could help boost the immune system to suppress tumor growth.

and his colleagues at first thought that DLPC would provide a useful tool in studying the function of a receptor protein – liver receptor homolog -1 or LRH-1 – that regulates the production of bile ...

The authors of a 2022 review article suggest that liver disease can increase bile salts, which then gather under the skin, resulting in pruritus. The body makes bile salts from bile acids.

Figure 4: Bile acid concentrations ... Student's t-test, and the null hypothesis was rejected at the 0.05 level. Tranche, T. et al. Hepatocyte nuclear factor-1 (HNF1) and liver gene expression.

Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids ...