Strategies for genetic transformation of RTCs with CRISPR/Cas9 constructs and regeneration of edited lines and the bottlenecks encountered in their establishment are also discussed. Certain attributes ...

Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran 1449614535, Iran Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran University ...

to target individual pieces of RNA (unlike the more widely known CRISPR-Cas9, which targets DNA). Typically, CRISPR is used to slice and edit genetic code, but in this case the researchers didn’t want ...

to target individual pieces of RNA (unlike the more widely known CRISPR-Cas9, which targets DNA). Typically, CRISPR is used to slice and edit genetic code, but in this case the researchers didn ...

This study offers valuable insights into the conformational dynamics of the nucleic acid recognition lobe of GeoCas9, a thermophilic Cas9 from Geobacillus stearothermophilus. The authors investigate ...

When CRISPR was first introduced as a gene-editing tool in 2012, the world was in awe of all the possibilities it held — eventually earning its discoverers the Nobel Prize in Chemistry in 2020. Now, ...

News broke yesterday that researchers in Philadelphia appear to have successfully treated a 6-month-old baby boy, called KJ, with a personalized CRISPR gene ... ammonia would build up to dangerous ...

An infant in Philadelphia has been successfully treated with a customized Crispr gene-editing therapy for a rare and deadly disease, doctors reported Thursday—a breakthrough in the futuristic ...

They would use a technology known as CRISPR, a personalized gene-editing therapy, to find the one uniquely mutated gene out of 20,000 in his little body, and fix it. KJ subsequently received three ...

A baby boy with a devastating genetic disease is thriving after becoming the first known person to receive a bespoke, CRISPR therapy-for-one, designed to correct his specific disease-causing mutation.

Within 6 months, a team of scientists designed and manufactured a customized CRISPR gene-editing therapy ... in the conversion causes ammonia to build up to levels that can damage organs such ...

KJ Muldoon, of Clifton Heights, is among the first to be successfully treated with a personalized CRISPR therapy ... cause deadly levels of ammonia to build up in the blood, leading to severe ...