Chagas cardiomyopathy is the most serious and frequent manifestation of Chagas disease. Clinical manifestations vary widely according to the severity of myocardial dysfunction, ranging from ...

A holistic approach to a clinically pertinent question that could pump-prime clinical and translational research and facilitate the introduction of precision medicine interventions both for stable ...

PH attributable to lung diseases and hypoxia; (4) chronic thromboembolic PH; and (5) PH with unclear/multifactorial mechanisms. 3 Until 2013, PH-CHD was listed exclusively under group 1 according to 4 ...

Researchers developed a wearable pad that detects inflammation and cancer biomarkers in menstrual blood using smartphone ...

FRACTION-RCC: Innovative, high-throughput assessment of nivolumab + ipilimumab for treatment-refractory advanced renal cell carcinoma (aRCC). Biomarker analyses from the phase III CheckMate 214 trial ...

Important advances in the field research on FTD over the last decade have led to an impressive change in the clinical recognition of this disease. Future scientific efforts should focus on three major ...

To provide a comprehensive update of the clinical picture of lymphangioleiomyomatosis (LAM) using two large patient registries. Methods: A cross sectional questionnaire survey which included questions ...

Collaboration between oncology and rheumatology for clinical care and research will enhance understanding of these new disease entities. Cancer therapy has evolved dramatically in recent years with ...

Methods Pragmatic, multicentre, non-inferiority randomised clinical trial in patients suspected of non-traumatic pulmonary disease at the emergency department. Between 31 January 2017 and 31 May 2018, ...

cDirectorate of Infection, Guy's & St Thomas' NHS Foundation Trust, London, UK dDepartment of Paediatric Infectious Diseases, Alder Hey Children's NHS Foundation Trust, Liverpool, UK eRespiratory Unit ...

The term ‘undifferentiated connective tissue disease’ (UCTD) is generally used to describe clinical entities characterised by clinical and serological manifestations of systemic autoimmune diseases ...

It’s also called Berger disease. The condition is a rare form of chronic kidney disease that happens when a germ-fighting protein called immunoglobulin A (IgA) builds up in the kidneys and causes ...