T cells, move over. B cells are now reported, in a recent paper in Nature, to have their own immunological synapses with APCs. Only this time the antigen is whole and B cells don't keep it to ...

By contrast, naive B cells produce IL-10 when stimulated in a 'bystander' activation context through non-cognate interaction with an activated T cell (CD40 signalling only, independent of either ...

A promising lead has emerged from examining the interaction between the tumor and immune cells, including CAR T cells. The findings are published in the Blood Journal. It turns out that B-ALL ...

Axi-cel, tisa-cel, and brexu-cel were found comparable to other cellular therapy experiences for patients with B-cell ...

More information: Jonas Nørskov Søndergaard et al, Single cell suppression profiling of human regulatory T cells, Nature Communications (2025). DOI: 10.1038/s41467-024-55746-1 Provided by Osaka ...

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing ...

Decoy increases effectiveness of treatment in B-cell acute lymphoblastic leukaemia B-cell Acute Lymphoblastic Leukaemia ...