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What if the secret to staying young wasn't another costly cream or trendy supplement, but tamping down a messy kind of cell ...
ASCO heard data suggesting that cell therapy may be a way of treating glioblastoma, which has been long seen as incurable.
Electric vehicles leave behind mountains of dead lithium-ion batteries. A new “injection” brings them back to life ...
In a discovery three decades in the making, scientists at Rutgers and Brookhaven National Laboratory have acquired detailed ...
Zika virus uses host cell autophagy to suppress antiviral proteins AXL and TIM-1, enhancing its ability to infect without ...
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in ...
Understanding the molecular mechanisms driving osteocyte death is crucial to developing ... which drives excessive autophagy and ferritin degradation, leading to intracellular iron overload ...
STING also triggers noncanonical autophagy, involving LC3 lipidation on STING vesicles through the V-ATPase-ATG16L1 axis, as well as induces cell death. Although the proton pump V-ATPase senses ...
Some of the different types of programmed cell death (PCD) include necroptosis, pyroptosis, apoptosis, and autophagy. Recent studies have provided a better understanding of the mechanisms ...
However, cell death was not inhibited by inhibitors of the other types of PCDs. Hence, they ruled out autophagy, necroptosis, and apoptosis, confirming that paraptosis is a major PCD pathway ...
autophagic cell death, and necrosis. Apoptosis occurs naturally in various contexts, such as during fetal development and when cells program themselves to turn off once they’ve aged. In autophagy, ...
However, deregulated autophagy triggers cell death. A wide array of research studies support the crucial role of autophagy in a variety of diseases. Cell death instigates the pathogenesis of several ...