Mouse models treated with the sleep aid lemborexant had less brain damage compared to controls and mice that received a ...

Anti-aging aficionados have tried it all — including taking certain drugs off-label in the hopes they will lead to longer, ...

A cocktail of FDA-approved cancer drugs, trametinib and rapamycin, boosts the lifespan of lab mice by 30% and might help ...

In a new study out this week, scientists report that a combination of two existing cancer drugs — rapamycin and trametinib — ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and Friedreich's ataxia.The ...

Matt Lafleur, who was told he had Friedreich ataxia as a child, is now on a mission of hope and advocacy for others. This story contains Matt Lafleur’s personal experience with SKYCLARYS ...

I will detail a new mouse model of A-T that develops many of the key characteristics of A-T, most importantly the progressive ataxia and associated defects and atrophy of the cerebellum. Additionally, ...

Patients and mouse models experience many kinds of abnormal movements when their cerebellum is damaged. They can have uncoordinated and unbalanced movements, called ataxia. They can have atypical ...

Patients and mouse models experience many kinds of abnormal movements when their cerebellum is damaged. They can have uncoordinated and unbalanced movements, called ataxia. They can have atypical ...

Specifically, they show that (1) different mouse models of cerebellar disease exhibit different ... The authors examine multiple distinct forms of different diseases, including different types of ...