Astrocytes transport the vast majority of extracellular glutamate (especially neurotransmitter ... neurons and converted to pyruvate for energy metabolism. [1] Astrocytes have an important role ...

Astrocytic glutamate uptake drives glycolysis and subsequent shuttling of lactate from astrocytes to neurons for oxidative metabolism. Astrocytes also convert synaptically reclaimed glutamate to ...

A research team at the University of Barcelona's Institute of Neurosciences (UBneuro) has discovered new molecular mechanisms ...

The human brain contains about 86 billion neurons. These cells fire electrical signals that help the brain store memories and ...

Our study investigated the role of astrocytes, an abundant cell type in the brain, in regulating an immune response against ...

Astrocytes are star shaped cells that make up around 35% of human brain cells. They were once thought of as cells that simply supported neurons... | Cell And Molecular Biology ...

Neuroinflammation contributes to the loss of dopamine neurons and motor dysfunctions in Parkinson's disease (PD). How cell metabolism regulates neuroinflammation by modulating epigenetic modifications ...

Glutamate plays a pivotal role in human metabolism. It provides a critical link between carbohydrate and amino acid metabolism. Glutamate is the obligatory precursor of glutamine; it plays a ...

"After deleting Mitch, we examined, every few hours, the effect that it had on more than 100 substances taking part in metabolism in human cells," said lead researcher Sabita Chourasia.

We are indebted to Dr. Jesse Greenstein for a supply of sterile arginine hydrochloride solution and to the Sherman Laboratories for the sodium glutamate solution. † Associate professor of ...

lipid metabolism, and as salient observation the upregulation of Pde10a. Our data suggest two possibilities: either APOE from the astrocytes acts directly on amyloid plaque formation and then ...