However, we now know that astrocytes have diverse and significant roles in glutamatergic signaling. Astrocytic glutamate transporters are the primary controllers of ambient extracellular glutamate ...

Astrocytes transport the vast majority of extracellular glutamate (especially neurotransmitter ... neurons and converted to pyruvate for energy metabolism. [1] Astrocytes have an important role ...

Ezrin deficiency affects glutamate metabolism and alters the shape of astrocytes Histological methods and proteome analyses were able to demonstrate that the lack of Ezrin alters important cell ...

“The results are very clear, you know, very convincing,” says Yongjie Yang, professor of neuroscience at Tufts School of Medicine in Boston, Massachusetts, who has studied the role of astrocyte ...

The slice was fixed and immuno-stained with an anti-GFAP antibody (grey). Astrocyte activity and metabolism is heavily integrated with neuronal activity. While classically, we think of astrocytes as ...

Image Credit: Kateryna Kon/Shutterstock.com The role of astrocytes in brain circuitry function, such as swift glutamate release, has been questioned due to inconsistent data and lack of direct ...

That study appeared June 26 in Neuron. An astrocyte listens in to the chemical conversation between neurons, soaking up neurotransmitters such as glutamate, the researchers showed. Astrocytes ...

"Astrocytes serve many functions in the brain but one of the most important ones is the removal of the neurotransmitter glutamate." Glutamate is the primary neurotransmitter that nerve cells in ...

In some mice, they disrupted the astrocytes' ability to soak up the neurotransmitter glutamate, a chemical that excites neural activity when it is received at connections called synapses.

It woke up the astrocytes the same way the genetic tweak had. It also restored normal glucose metabolism in the hippocampus, an area that's critical to memory and navigation. And once a mouse had ...

[49] Glutamate excitotoxicity ... declared they have no competing interests. Astrocytes perform critical roles in amino acid, nutrient and ion metabolism in the brain, coupling of neuronal ...