Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies.

EpiVax, Inc. announces a new study published in Frontiers in Immunology unveiling the impact of peptides known as "Tregitopes ...

we have improved the resolution of antigen arrays down to the epitope level. In this analysis, three distinct patterns of antibody reactivity were identified: (i) peptides that were differentially ...

Determining how to predict the antibody-antigen interactions was the biggest ... it could produce 3D structures for more than just one dominant epitope. The predictions were validated against ...

In the landmark Amgen v. Sanofi case (previously covered here), the Supreme Court affirmed that patent claims drawn to a genus of ...

YUMAB uses libraries of close to germline origin, but highly diverse antigen ... whole antibody-discovery process in vitro and bypassing animal immunization, YUMAB eliminates potential epitope ...

AK0610 is engineered from an antibody isolated from a recovered infant and targets the pre-fusion F protein of RSV. It has a unique viral antigen binding epitope and a new mechanism of action.

The antibody 7E11 binds to the intracellular epitope ... Grimm J (2011) Targeting the internal epitope of prostate-specific membrane antigen with 89 Zr-7E11. J Nuclear Med 52(10):1608-15.

He also researched and developed antigens that could be used ... the display of a highly conserved single epitope from HPV L2 protein, on one of the surface-exposed loops of a bacteriophage VLP, ...