B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

Recent advances in cancer research have underscored the critical role of myeloid cells in shaping tumor microenvironments ...

It might also be beneficial to combine anti-angiogenic agents with multifunctional adipokines such as leptin. For example, whereas other inhibitors could block leptin-induced angiogenesis in ...

Angiotensin-converting enzyme inhibitors (ACEis) are known to have antifibrotic effects ... in rats treated with the ACEi captopril either alone or combined with an ...

Abstract: CXCR7, a G-protein-coupled chemokine receptor, has recently emerged as a key player in cancer progression, particularly in driving angiogenesis and metastasis. Despite its significance, ...

School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, PR China Key Laboratory of New Drug ...

Specific blockade of DLL4, alone or in combination with other angiogenesis inhibitors, provides the exciting possibility of benefiting patients with tumours that are resistant to anti-VEGF therapies.

Combination therapy did not provide a benefit in the overall cohort of patients with recurrent ovarian cancer or when patients were evaluated according to BRCA status. Combination treatment with a ...

Long noncoding RNAs and glycolytic enzymes have emerged as critical regulators of angiogenesis, linking metabolic activity with vascular expansion. Anti-angiogenic therapies, including VEGF inhibitors ...

Molecular Pharmacology Section, Cancer Therapeutics Branch and Clinical Pharmacology Research Core, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, ...

Conclusion: The harmine derivative B-9-3 may exert its anti-NSCLC effects by inhibiting angiogenesis and promoting lung cancer ... Efficient RIPA tissue/cells fast pyrolysis liquid, protease ...

Read the full abstract... Objectives: To assess the effects of proton pump inhibitors on the prevention of dyspepsia and ulcers in people with chronic consumption of non-steroidal anti-inflammatory ...