Scientists have long believed they understood how life’s genetic code evolved, but new research upends that assumption. By ...
8). Figure 1: A sequence alignment of amino-acid residues near the H-9 (α9) and H-10 (α10) helix of class C β-lactamases with extended substrate spectrum.
Using Geneious software, the amino acid sequences of the V and J genes were aligned and structurally segmented. Based on the conserved amino acid motifs in the FRs and CDRs recognized by MiXCR, in ...
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By listening, scientists learn how a protein foldsHydrogen bonds are relatively weak attractions that align atoms located on different amino acids in the protein ... researchers wanted to map the time sequence of hydrogen bonds that occur ...
Stanford researchers introduced affordable gene-editing kits ready for the classroom, aiming to make the field more accessible for high school students.
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Our statistical results align with these expectations (Table 1 ... When the temperature sample was set at 0.1, 139 positions recovered to the same amino acids as the wild-type sequence, while the ...
The unexpected finding of several single-point mutants with an improved affinity for CO 2 demonstrates that the relationship between the amino-acid sequence of rubisco and its enzymatic function ...
In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...
Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance
How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA clearance following damage, driven by the exonuclease activity of the mtDNA ...
This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...
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