This manuscript introduces a useful protein-stability-based fitness model for simulating protein evolution and unifying non-neutral models of molecular evolution with phylogenetic models. The model is ...

Another factor that may be contributing to the decline in publishing by industry medicinal chemists is the fact that ...

Viral infectious diseases pose significant challenges due to the rapid evolution of viruses through mutations. This was particularly evident during the COVID-19 pandemic, when emerging variants of ...

"With this new equation, we can simulate larger protein complexes and gain deeper insight into how these molecular machines ... You can change one amino acid and see how the mutation affects ...

Researchers have developed a novel compound that could be useful for treating bone-destructive diseases. Their study ...

The breakdown of glutamine is an important metabolic pathway for the health and survival of rod photoreceptors within the retina.

Purdue University scientists have discovered a key mechanism that regulates how plants develop chloroplasts, essential ...

New research from the Sainsbury Laboratory at the University of Cambridge has shed light on how plants precisely control ...

Inspired by how DNA can pack massive quantities of information into tiny amounts of material, chemists have been working for ...

Their relevance within the domain of gut science continues to intrigue researchers due to their diverse properties and ...

Computer simulations help materials scientists and biochemists study the motion of macromolecules, advancing the development ...