The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

The UCL School of Pharmacy has a long history of characterisation of alternative DNA structures, from the first crystal structure of a different DNA structure called a G-quadruplex, in a 2011 ...

During DNA replication, the classic double helix can temporarily rearrange into an alternative structure known as a DNA three ...

Alternative DNA structures, such as left-handed Z-DNA, hairpin DNA, cruciform DNA, slipped-stranded DNA, parallel-stranded DNA, unpaired DNA, mirror-repeat DNA, palindrome DNA, and folded slipped ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred to as non-B DNA—have been implicated as regulators of cellular ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a ...

This research provides a promising new approach to treating patients with relapsed ovarian cancer and adds to growing evidence that DNA's alternative structures could be powerful targets in the ...

Shankar Balasubramanian is thinking beyond DNA’s four-letter code Coinventor of next-generation sequencing has widened his focus to DNA’s large-scale structures and molecular modifications ...

The function of this form is to protect DNA. DNA will revert to this type when it's dehydrated. Z-DNA has a left-handed double helix structure. It is said to be found during the start of a gene.

Researchers, led by Penn State biologists, have comprehensively predicted the location of potential non-B DNA structures in the newly available telomere-to-telomere genomes of the great apes.