The pre-B-cell receptor (pre-BCR), which comprises two Igμ chains and two germline-encoded surrogate light chains (SLC) that are associated with the signalling ... suggest a model that could ...

Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Scientists used high-resolution 3D X-ray imaging to uncover major structural and immune changes in the gut of Alzheimer's ...

Evidences in many cancers suggest the following model of SC transformation ... through BMP signaling that simultaneously controls SCs and neighboring cells. In the presence of treatments, this ...

We have shown that obexelimab inhibits the phosphorylation of BTK, thereby interfering with BCR signalling. Objectives: The aim of this study is to examine the molecular effects of obexelimab on B ...

CIRBP Family, Tumors, Molecular Mechanisms, RNA-Binding Proteins, Cellular Stress Share and Cite: Cai, Y. , Wang, T. and Zhan ...

In this study, we utilized this model and ... CD8 memory T cells expressed anti-apoptotic genes. Thus, the transcriptional analysis of gene expression and signaling pathways in aged T cell subsets ...

exhaustion of T cells, altered B cell antigen presentation, and reduced NK cell maturation and cytotoxicity. Transcriptomic analysis reveals that fewer pathways and transcription factors are activated ...

The following highlights showcase the most pivotal, innovative research published across multiple therapeutic areas in ...

Despite research showing the benefits of circulating tumor DNA as an indicator of disease remission in B-cell lymphoma, ...