You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

In parallel, exposure to naringin enhanced translocation of estrogen receptor alpha (ERα) to nuclei and its transactivation ... attenuated naringin-induced augmentations in ERα transactivation ...

We describe a family with a history of breast and ovarian cancer in which MLPA analysis of the BRCA1 gene pointed to a deletion including a part of exon 11. Further characterization confirmed a loss ...

LIfT BioSciences presents latest data on its first-in-class Immunomodulatory Alpha Neutrophils at International Society for Cell and Gene Therapy London, 19 May 2025- LIfT BioSciences, ('LIfT' or 'the ...

Background: Chromosome 16p13.3 deletions cause a contiguous gene deletion syndrome, ATR-16 syndrome. The classic phenotype of ATR-16 syndrome includes either alpha-thalassemia trait or hemoglobin H ...

Edited by Caroline S. Harwood, University of Washington, Seattle, WA, and approved October 7, 2014 (received for review July 20, 2014) ...

Thalassemia occurs when there is a mutation or deletion in the genes that code for these globin chains. Depending on which chain is affected, it is classified as: Alpha-thalassemia: Caused by ...

DURHAM, N.C.--(BUSINESS WIRE)--Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company utilizing its novel proprietary ARCUS® platform to develop in vivo gene editing ...

CRISPR Therapeutics AG (CRSP) is a biotech firm pioneering gene-editing therapies leveraging ... compensation for it (other than from Seeking Alpha). I have no business relationship with any ...

The first possibility is ruled out, as the effect is seen in cells from individuals with a variety of mutations, including those with no protein due to partial gene deletions. The other two ...

However, co-inheritance of β-thalassemia and δ-globin gene mutations may affect the diagnosis of β-thalassemia carriers when based on the elevated Hb A 2. This study aimed to identify and characterize ...