Without alpha globin, hemoglobin cannot carry oxygen ... Multiplex Ligation-dependent Probe Amplification, which detects deletions or duplications in gene copies "These tests are particularly ...

“A person normally inherits four alpha globin genes, two from each parent ... Multiplex Ligation-dependent Probe Amplification, which detects deletions or duplications in gene copies “These tests are ...

Researchers at the University of California, Davis, have deleted a cluster of genes in wheat that generates ... gamma radiation to target and delete alpha-gliadins, which can cause severe ...

this putative migration rate is 20-fold higher than that currently estimated from other genes, and would correspond to a non-realistic minimal current admixture of 80%. thus, our results suggest ...

First up, the lentiviral vector that delivers the gene seems to be working as expected, with expression of the replacement β-globin gene HbAT87Q present at therapeutic levels (44% to 59% ...

DURHAM, N.C.--(BUSINESS WIRE)--Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company utilizing its novel proprietary ARCUS® platform to develop in vivo gene editing ...

However, co-inheritance of β-thalassemia and δ-globin gene mutations may affect the diagnosis of β-thalassemia carriers when based on the elevated Hb A 2. This study aimed to identify and characterize ...

Background: Chromosome 16p13.3 deletions cause a contiguous gene deletion syndrome, ATR-16 syndrome. The classic phenotype of ATR-16 syndrome includes either alpha-thalassemia trait or hemoglobin H ...

Four down-regulated genes from the SSH procedure, with potential roles in the hosts' immune and inflammatory response to ALV infection, were selected for confirmation of differential expression.

CNVs range widely in size from single genes to large segmental deletions or duplications of millions of base pairs. In general, deletions are more deleterious than duplications because of the ...