Purpose: Down syndrome (DS) is a developmental disability associated with difficulties in deglutition. The adult Ts65Dn mouse model of DS has been previously shown to have differences in measures of ...

Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München—German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, D-85764 ...

Lung tissue homogenate was used for ELISA to determine the IL-1β concentration. ELISA was performed according to the manufacturer’s guidance (IL-1β Mouse Uncoated ELISA Kit, Invitrogen, #88-7013-22, ...

Moreover, to gain mechanistic insights into the mode of gelsolin activity, a series of biochemical analyses was performed ex vivo in mouse embryonic fibroblasts. Results: Increased gelsolin expression ...