A protein identified nearly 40 years ago for its ability to stimulate the production of red blood cells plays a surprising, ...

Get Instant Summarized Text (Gist) A comprehensive spatiotemporal atlas of developing mouse lungs has been constructed, revealing new molecular and cellular mechanisms in pulmonary organogenesis ...

These data identify HMGB1-RAGE as a novel regulator of ILC2s promoting type 2 inflammation in the lungs following HS. A mouse HS and resuscitation model was created as described previously.7 17 In ...

In idiopathic pulmonary fibrosis (IPF) patients, alveolar epithelium architectures are persistently lost and lung gas transfer function would decline over time, which cannot be rescued by conventional ...

Introduction: Arsenic (As) exposure is associated with lung toxicity and we aim to investigate the effects of arsenic exposure on lung fibrotic changes. Discussion: we demonstrated that continued ...

Then they wanted to know if they could selectively incorporate the enhancer elements into an adult mouse using adeno-associated virus, a familiar gene therapy tool for introducing gene sequences into ...

Here, we demonstrate APEX2 proximity labeling within genetically targeted neurons in the mouse brain, enabling subcellular proteomics with cell-type specificity. By combining APEX2 biotinylation with ...

Alveolar architecture plays a fundamental role in the processes of ventilation and perfusion in the lung. Alterations in the alveolar ... fixation (SAF): This method is the gold standard in histology ...