S-acylated proteins can undergo reversible cycles of S-acylation and de-S-acylation with timescales ranging from seconds to hours. 8 The S-acylation reaction is catalyzed by zDHHC (zinc finger ...

This valuable paper presents a new protocol for quantifying tRNA aminoacylation levels by deep sequencing. The improved methods for discrimination of aminoacyl-tRNAs from non-acylated tRNAs, more ...

Zealand Pharma has patented a method for producing acylated glucagon analogue peptides for treating obesity, diabetes, and metabolic disorders. The compound formula includes specific peptide sequences ...

Background/Aims: The gastric peptide ghrelin, an endogenous ligand for growth-hormone secretagogue receptor, has two major molecular forms: acylated ghrelin and desacyl ghrelin. Acylated ghrelin ...

Zealand Pharma has patented a method for producing acylated glucagon analogue peptides for treating obesity, diabetes, and metabolic disorders. The compound formula includes specific peptide sequences ...

Acylated peptides composed of glucagon-like peptide-1 receptor agonists modified with a fatty acid side chain are an important class of therapeutics for type 2 diabetes and obesity but are susceptible ...

Here, we found that ROT4 is S-acylated for its membrane localization in plant cells. S-acylation, also denoted S-palmitoylation, is an important post-translational modification that transfers ...

Hippuric acid, or N -benzoylglycine, is an amino acid derivative found in the urine of herbivorous animals. The name is derived from Greek hippos (horse) and ouron (urine). In 1829, the pioneering ...

Anthocyanins, especially acylated ones in purple vegetables, can reduce type 2 diabetes risk by improving gut health, metabolism, and inflammation control. According to a recent review article that ...

Acylated compounds move through the body, starting at the upper gastrointestinal tract and traveling down to the colon. Once they reach the colon, gut microbes break down and metabolize them. The ...

Acylated anthocyanins are poorly absorbed in digestion, but they have probiotic properties and reduce the risk of diabetes more efficiently than nonacylated anthocyanins.