The neurotransmitter acetylcholine is an essential chemical communicator, carrying impulses from neurons to skeletal muscle cells and many parts of the nervous system. Now researchers at the ...

Its chemical structure is similar to that of organophosphates, a common class of insecticides, which contain carbon-based groups coupled to a phosphorous atom.

IN spite of the simplicity of its chemical structure, details of the mode of action of acetylcholine (ACh) remain unknown. We have considered stereochemical attachment of ACh at its nicotinic and ...