These drugs are called agonists. They don't cause neurotransmitter levels to rise but instead increase activity by stimulating receptors. GABA agonists include: Yoga is generally believed to be ...

These receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action. There are two main endocannabinoid receptors: CB1 receptors ...

It acts on more than 65 receptors in your brain, some of which affect your levels of serotonin. That’s a brain chemical that helps control your mood. Several drugs already used to treat anxiety ...

Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. 4,5 Here, we review ...

Get Instant Summarized Text (Gist) A 2016 bird flu variant was found to be one mutation away from binding to human receptors, highlighting the potential for avian influenza to adapt to humans. The ...

During maturation, certain T cells will develop a protein on their surface called CD4. CD4 proteins act as receptors to recognize "foreign" agents that are presented in a particular context on the ...

One of the primary mechanisms of SCFA benefits was the direct activation of a group of G-protein-coupled receptors (GPCRs), termed free fatty acid receptors (FFARs), the FFAR2 (GPR43), and FFAR3 ...

Pfizer Inc. (NYSE: PFE) today announced the decision to discontinue development of danuglipron (PF-06882961), an oral glucagon-like peptide-1 (GLP-1) receptor agonist, which was being investigated ...

This patent highlight describes a series of novel 2-pyrrolidone derivatives that act as negative allosteric modulators (NAMs) of GluN2B-containing N-methyl-d-aspartic acid receptors (NMDARs). These ...

College of Plant Protection, Nanjing Agricultural University/State & Local Joint Engineering Research Center of Green Pesticide-Invention and Application, Nanjing 210095 Jiangsu, China ...

The combined action of DP 1 and CRTH2 have a fundamental role in the polarization of T cells to the T H 2 phenotype and their subsequent recruitment and activation. Pharmacological studies with ...