Announcing the 2025 HDBuzz Prize for Young Science Writers – sponsored by the Hereditary Disease Foundation!

From vision changes to genetic traffic jams and a clinical trial update, May was full of HD science excitement! Dive into our latest roundup to see how researchers are advancing Huntington’s ...

In cells without the HD gene, HTT stimulates PARylation and promotes efficient DNA repair. However, in HD, the mutant HTT protein fails to stimulate PARP, leading to fewer PAR chains, impaired DNA ...

Seeking dental care and adhering to recommended routines is tough for lots of folks, even under the best of circumstances. Throw Huntington’s disease (HD) into the mix, and oral health can get even ...

Prana Biotech's PBT2 trial in Huntington's disease: what we know so far & what copper has to do with the mutant prote ...

Huntington's disease mice are fat but HD patients lose weight – is a brain area called the hypothalamus to blame?

Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie ...

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

A clinical trial for an exciting therapy against HD is planned for 2015. The first step is to make sure it is safe.