TFIID enables RNA polymerase II promoter-proximal pausing. Mol Cell 2020, 78: 785 – 793. Schier, AC; Taatjes, DJ. Structure and mechanism of the RNA polymerase II transcription machinery. Genes Dev.

An RNA polymerase II molecule is about 15 nanometers across, or roughly 5,000 times smaller than the width of a human hair. This image was created by reconstructing X-ray diffraction crystallography ...

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase ... I transcribes ribosomal RNAs (rRNAs), RNA pol II transcribes RNAs that will become messenger RNAs ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

Overview of RNA ... (ii) developing a kinetic mechanism for the healing and sealing steps; (iii) highlighting distinctive kinetic properties and NTP specificities of the kinase components of fungal ...

For the first time, researchers have visualized the three-dimensional structure of the Nipah virus's RNA polymerase—the ...