Cancer immunotherapy represents a transformative approach in oncology, especially for treating cancers thought to be incurable. However, a significant ...

To support messenger RNA (mRNA)-based vaccines and therapies, Thermo Scientific POROS Oligo (dT)25 affinity solution was designed for the purification and isolation of mRNA of in vitro transcription ...

This process is repeated until all the codons in the mRNA have been read by tRNA molecules ... and must exit the nucleus to be translated; these multiple steps offer additional opportunities ...

Then, a process called translation uses this mRNA as a template for protein assembly ... the initiation phase of translation is complete. The next step in translation, called elongation, begins ...

The resulting primary transcript, known as pre-mRNA in eukaryotes, undergoes several processing steps before becoming a mature mRNA molecule: After processing, the mature mRNA is transported from the ...

Researchers at the University of Würzburg have discovered a process that breaks down mRNA molecules in the human body particularly efficiently. This could be useful, for example, in the treatment ...

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification, including alternative polyadenylation, circularization and RNA methylation. As a core member of ...

Exporting the mRNA from inside the nucleus to the site of protein translation in the cytoplasm is a critical step for life for eukaryotes like us. Yi Ren's most recent paper, published in eLife ...

with the 3 rd mRNA Process Development & Manufacturing Summit 2025—Europe’s premier industry-focused forum dedicated to optimizing mRNA therapeutics and vaccine development. The official event ...

Enhance Speed, Purity & Scalability of Your Process Development & Manufacturing to Improve Functionality, Efficacy & Approval Rate of mRNA Drugs Across All Disease Indication Returning to ...