The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely ...

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely ...

The molecular pathways involved in antiviral defenses and counter-defenses in host-pathogen systems remain unclear. Researchers have used Neurospora crassa as a model organism to explore how RNA ...

Following the COVID-19 pandemic, mRNA-based vaccines have been shown to provide rapid and precise immune responses, however, this technology has much wider applications. Many leading pharma and ...

Lipid nanoparticle (LNP) mRNA vaccines emerged during the COVID-19 pandemic to form an almost miraculous protection against a virus, which killed millions around the world. Aided by expedited ...

In this article we give an overview of RNA-based HPV diagnostics and the role of E6/E7 mRNA detection as a predictive marker for the development of cervical carcinoma. HPV E6/E7 mRNA testing for ...

and its therapeutic potential following the successful use of pseudouridylation in SARS-CoV-2 mRNA vaccines. Recent work shows that m6A RNA methylation is an important regulatory mechanism during ...

In this study, the authors report a single cycle-replicating SARS-CoV-2 vaccine candidate virus (ΔEM) and show that it induces spike-specific IgA and CD8+ T cells targeting spike and nucleocapsid ...

To determine whether differential mRNA turnover contributed to the differences in competition and response to SBP2, mRNA half‐lives were determined. Cells were transfected with constructs encoding the ...