Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

Researchers at the Max Planck Institute for Evolutionary Anthropology have addressed a longstanding challenge in CRISPR ...

multiple factors and elements were shown to coordinate transcription and translation, suggesting an intricate level of synchronization. This review discusses the molecular mechanisms that impact both ...

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell nuclei of all flora and fauna. In addition to exporting materials out of the ...

The mechanism differs in eukaryotes and prokaryotes. Eukaryotes genes are regulated by transcription factors (a type of protein) which bind to a region known as the promoter region found just before ...

In eukaryotes, multiple transcription factors (TFs) bind to regulatory DNA regions to control gene expression, where adjacent TF binding exhibits positive or negative cooperativity (enhancing or ...

By binding to the promoter site on a DNA strand, RNAP along with transcription factors form a transcription pre-initiation complex (PIC). This initiates the process of transcription. The promoter ...

All major biological processes start after protein molecules known as transcription factors detect specific regulatory sequences on DNA and initiate genetic expression by associating to them. But in ...

Gene expression is regulated by both internal and external factors – a perfect interplay ... It consists of two major steps: transcription and translation. These steps differ in prokaryotic and ...

Eukaryotic Spt5 couples processive transcription to the efficient capture and re ... were analysed by immunoblotting of the indicated factors. The asterisk indicates a non‐specific band in the ...

A subset of eukaryotic transcription factors (TFs) possess the ability to reprogram one cell type into another. Genes important for cellular reprograming are typically located in closed chromatin, ...

Qatar Higher eukaryotic development is a complex and tightly regulated process, whereby transcription factors (TFs) play a key role in controlling the gene regulatory networks. Dysregulation of these ...