How did eukaryotic organisms become so much more complex than prokaryotic ones, without a whole lot more genes? The answer lies in transcription factors. Experiments have shown that TFs can bind ...

In eukaryotes, termination is more complex and involves additional factors that help to release the RNA polymerase and the newly synthesized RNA molecule. mRNA is the most common type of RNA produced ...

Gene expression is regulated by both internal and external factors – a perfect interplay ... It consists of two major steps: transcription and translation. These steps differ in prokaryotic and ...

By binding to the promoter site on a DNA strand, RNAP along with transcription factors form a transcription pre-initiation complex (PIC). This initiates the process of transcription. The promoter ...

The regulation of mRNA transcription plays a key role in relaying signals from the environment and during development into the gene expression program of a cell. During transcription initiation, a ...

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell nuclei of all flora and fauna. In addition to exporting materials out of the ...

Within all complex, multicellular living systems such as plants and humans, there exists a set of genetic elements that can be likened to the blueprints, tools, and specialized personnel at a ...

He then did a three-year post-doctoral position at the University of Portsmouth investigating eukaryotic transcription factors involved in blood development. In 2000, he moved to the Animal Health ...